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Domenii Medical Pneumologie / O.R.L.

PARI Provocation Test IIPari

793000 leiIn stoc Înapoi
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Unspecific bronchial provocations play an important part in diagnosis, therapy monitoring, and for scientific, expert and occupational medicine issues [2, 3].

The facts supporting the effectiveness of the PARI PROVOCATION TEST® II are convincing
• Recommended by the German Society for Pneumology [1]
• Provocation with a single concentration
• Validated provocation reports available

The PARI PROVOCATION TEST II - the system of choice according to the guidelines of the German Society for Pneumology - is particularly well suited for quantitative, unspecific provocation with methacholin, carbachol or histamine.

The PARI PROVOCATION TEST II enables statements to be made regarding the quantity of test substance inhaled. Quantification is assured by the adjustable aerosol volume in the aerosol bag containing up to 10 litres. A special nebuliser ensures that mostly small aerosol drops are able to reach the storage bag.

The patient takes deep vital capacity inspiratory breaths through a 2-way system until the storage bag is empty. In this way, the act of inhaling and the individual anatomy of the respiratory tract have very little influence on the quantity of aerosol deposited because of the optimised droplet spectrum [4].

The quantity of the provocation substance deposited in the lungs can be calculated directly in µg or mg. Validated provocation reports and associated evaluation charts are available for methacholin, carbachol and histamine.
When the patient inhales slowly and deeply (see figure) an average 86% of the quantity output at the mouthpiece is deposited in the lungs. Only about 11% is exhaled and less than 3% is deposited in the mouth.

Literature:
[1] Leitlinien für die Durchführung bronchialer Provokationstests mit pharmakologischen Substanzen, Arbeitskreis "Bronchiale Provokationstests" in der Deutschen Gesellschaft für Pneumologie. Pneumologie 52 (1998), 214-220
[2] Fischer JF, Unspezifische und spezifische Provokation bei Asthma bronchiale. Atemw.-Lungenkrkh. 29 (2003), 493-494.
[3] Klein G et al., Empfehlungen zur Durchführung Bronchialer Provokationtests mit pharmakologischen Substanzen. Medizinische Klinik 92 (1997), 458-463
[4] Köhler D, Problematik der dosisgenauen Inhalation, dargestellt am Beispiel des Provokationstestgerätes I. Pneumologie 45, Sonderheft 2 (1991), 659-669

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